|What is the most explosive and energy releasing combination of chemicals? — RC, Chapman, Australia
A mixture of 1 part hydrogen and 19 parts fluorine by weight is the most energetic possible mixture of chemicals, releasing approximately 13,600 joules of energy per gram. The next most potent mixture is 8 parts oxygen and 1 part hydrogen by weight, releasing approximately 13,400 joules of energy per gram. Because fluorine is such a vigorous oxidizer that tends to cause fires, it isn't practical for rocket propulsion. The hydrogen/oxygen mixture is the basis for the Single Stage to Orbit rockets that are currently being developed. — Thanks to Gary V. Lorenz at NASA for help on this question.